Additional tools for quickly and accurately assembling genomes of any size using a reference on a desktop computer.
SeqMan® NGen® software for next-generation sequence assembly, Lasergene® Core Suite for post-assembly analysis, ArrayStar® software for large-scale, multi-sample SNP analysis, and QSeq® software for ChIP-Seq, RNA-Seq and miRNA analysis.With DNASTAR® Lasergene® Genomics Suite Software You Get: Our software uses a proprietary algorithm to quickly and accurately assemble a genome of any size using a reference on a desktop computer, and includes a comprehensive suite of post-assembly analysis tools, including SNP detection and analysis, evaluation of coverage, consensus annotation, and more.
Although the other modules can import.The DNASTAR® Lasergene® Genomics Suite provides all of the software you need for next-generation sequence assembly and analysis in a single, integrated package. Lasergene is compatible with BLAST versions 1.4 and 2.0 (which allows the introduction of gaps into the sequence alignments and is thus more sensitive, but slower).ĮditSeq is a sequence editor module for importing and exporting DNA and protein sequence files. Entrez sequence retrieval and BLAST searches are both configured in Lasergene to use servers at NCBI, although local versions of the programs can be employed if desired. BLAST can identify similarities between a nucleotide or protein sequence and other such sequences in the public databases. NCBI, established in 1988 as a national resource for molecular biology information, also provides the Basic Local Alignment Search Tool (BLAST), which is available from every module of Lasergene through a server at NCBI. Sequence files can be directly imported into each module, from the National Center for Biotechnology Information (NCBI) Entrez database, either by accession number or by locus name. Integration of Internet analyses within the various program modules is a major addition to Lasergene. The individual Lasergene99 modules are accessed through the Navigator, which also allows the user to access help files for the Lasergene99 suite. The rapid growth of the public sequence databases, and their availability online, makes the CD-ROMs unnecessary. Rather than the previous bimonthly release that included CD-ROMs with DNA and protein databases, the new version of Lasergene99 is released annually without the accompanying sequence databases. The entire package retains a modular format, which allows users to select only those modules useful for their work.
The most noticeable change in this update is the integration of Internet capabilities into the seven different modules that compose the Lasergene99 suite, although the user interface and selected modules have also been improved and a number of bugs have been fixed.ĭespite these changes, the Lasergene99 package is virtually identical in look and feel to the previous version. Last year, an update to this classic program named Lasergene99 was released. In recent years, this package has lost ground in the highly competitive market for sequence analysis packages. One of the most popular and powerful of these has been the Lasergene sequence analysis software suite published by DNASTAR. Comprehensive sequence analysis products provide alignment of DNA and protein sequences, primer design, sequence editing, secondary structure prediction, mapping, and database homology analysis. 60 As the sequencing of the human genome approaches completion, the task of analyzing and annotating the finished sequence will become increasingly important.